Posted on April 12, 2021
An Overview Of Monoclonal Antibody Preparation Technology
Monoclonal antibody technology is crucial in the scientific research of biotechnology, playing an indispensable role in the structure and function of genes and proteins, which keeps irreplaceable in the immunological diagnosis of human beings, animals, and plants.
Techniques for the production of monoclonal antibodies are presented below, including hybridoma technology and the construction of a phage view library with a broad perspective for use in clinical medicine as well as for the diagnosis and treatment of disease. Boster Bio featured products can provide the best antibody production services.
Latest technology updates
1. The traditional method
Chimeric monoclonal antibodies
- The CDR antibody graft antibody has a high human affinity of 95%.
- Humanization of amino acid residues on the three-dimensional surface of the antibody to humanize the cosmic surface of the variable region fragments.
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1.1 Hybridoma service from Creative Biolabs
Hybridoma technology, a widely accepted method for large-scale production of monoclonal antibodies resulting from the fusion of specific antibodies producing B lymphoblasts with myeloma, takes the formation of hybrid cell lines as a key element.
The Hyperdoma Creative Biolabs platform is a powerful hybridoma generation platform integrated with the latest technology to ensure the production of unique monoclonal antibodies by global customers.
Solutions include Magical Human Antibody Generation, DNA Immunization Based Hybridoma Generation Service, Custom Antibody Generation Service, Natural Antibody Detection Service, etc.
2.Phage Display Technology
Phage antibody library technology and ribosome display technology are the main approaches to antibody library screening technology. Phage antibody library technology is the most mature and widely adopted antibody library technology so far that is based on the ability of phage shells to express antibody-protein fragments.